Senior Director, Clinical Pharmacology & Pharmacometrics

Job overview

The Senior Director, Clinical Pharmacology & Pharmacometrics role is remote in the U.S. or onsite/hybrid in Palo Alto, CA. The anticipated base salary is $285,000–$325,000 per year, plus annual bonus, equity, and benefits. GondolaBio develops therapeutics for genetic diseases. The role sets and executes clinical pharmacology and pharmacometrics strategy across programs, informing dose selection and development decisions from investigational new drug stages through later development. It combines hands-on modeling and study work with functional leadership, regulatory engagement, and scientific communication.

What you'll do

• Own clinical pharmacology strategy and development plans
• lead first-in-human dose selection and escalation
• perform and oversee translational and mechanistic PK/PD modeling
• lead population PK, PK/PD, exposure-response modeling and simulation
• support nonclinical PK/PD, ADME, and DMPK evaluations
• design and interpret clinical pharmacology studies
• author and review regulatory documents
• represent the function in health authority interactions.

What we're looking for

Skills & competencies

senior director

clinical pharmacology

pharmacometrics

remote u.s.

hybrid

palo alto ca

gondolabio

$285k–$325k

oligonucleotide therapies

dose selection

pk/pd modeling

regulatory strategy

flexible pto

Work arrangement

• Weekend coverage required

Benefits & perks

• Annual bonus
• equity
• comprehensive benefits
• flexible PTO
• learning and development resources.

Why this role

PhD and 10+ years of industry clinical pharmacology and/or pharmacometrics experience required. Oligonucleotide therapeutics experience is strongly preferred; role includes hands-on modeling and leadership responsibilities.

About the employer

GondolaBio Service Co, Inc. is hiring for this role. Industry: Research and Development in Biotechnology (except Nanobiotechnology). Sector: 54.