Principal Research Scientist I, Biologics Process Analytics

Job overview

The Principal Research Scientist I, Biologics Process Analytics role is onsite in Worcester, MA. Compensation is not specified. The position supports AbbVie’s Late-Stage Process Analytics group within Analytical Development, advancing late-stage biologics programs and AbbVie’s mission to deliver innovative medicines. This scientist leads process analytics for monoclonal antibodies and drug substance, provides expertise in separation-based methods, and partners across development and manufacturing teams. The role advances program decisions through reliable testing, method development and troubleshooting, regulatory documentation, and mentorship of junior scientists.

What you'll do

• Lead process analytics for monoclonal antibodies and drug substance in CMC teams
• serve as a subject matter expert in HPLC, capillary electrophoresis, and related methods
• select analytical technologies
• support testing, method development, execution, and troubleshooting
• review results and communicate risks
• collaborate across R&D and product development
• prepare and review technical documents and IND/BLA analytical sections
• implement analytical techniques
• mentor or supervise junior scientists
• provide hands-on laboratory support as needed.

What we're looking for

Skills & competencies

principal research scientist

biologics

process analytics

analytical development

hplc

capillary electrophoresis

cmc

late-stage programs

gmp

worcester ma

abbvie

Work arrangement

• Weekend coverage required

Benefits & perks

• Paid time off, medical, dental and vision insurance, 401(k), and eligibility to participate in long-term incentive programs.

Why this role

Late-stage biologics development role with analytical leadership and regulatory submission responsibilities.

About the employer

AbbVie is hiring for this role. Industry: Research and Development in Biotechnology (except Nanobiotechnology). Sector: 54.