Senior Manager, Analytical Method Validation

Job overview

Compensation is $140,000–$160,000 per year. The Senior Manager, Analytical Method Validation role is onsite in Madison, WI; in the feed. The posting gives a Wisconsin pay range of $140,000–$160,000 per year. Arrowhead Pharmaceuticals develops RNAi-based medicines for diseases with a genetic basis; this role supports its Quality Control department. The manager leads scientists and provides technical direction for analytical method validation and transfer supporting oligonucleotide manufacturing samples, drug substances, drug products and stability testing. The role helps ensure methods are compliant, fit for purpose and reproducible, while coordinating projects and resolving analytical issues.

What you'll do

• Plan, author and execute validation protocols and reports
• lead method transfers between sites, laboratories and contract partners
• oversee validation and transfer for analytical techniques
• present strategies and data to internal stakeholders and external partners
• coordinate project timelines and deliverables
• troubleshoot method performance and support OOS/OOT investigations and root-cause analysis
• evaluate analytical technologies
• maintain compliant QMS documentation
• design experiments, analyze results, write technical documentation and review QC data.

What we're looking for

Skills & competencies

senior manager

analytical method validation

quality control

oligonucleotides

method transfer

gmp

madison wi

arrowhead pharmaceuticals

$140k–$160k/year

lc-ms

uhplc

hplc

qms

Work arrangement

• Weekend coverage required

Benefits & perks

• Competitive salary and an excellent benefits package.

Why this role

The posting lists a Wisconsin pay range of $140,000–$160,000 and requires relevant laboratory experience, including analytical methods for complex oligonucleotides and method validation or transfer in a GMP-regulated environment.

About the employer

Arrowhead Pharmaceuticals is hiring for this role. Industry: Biological Product (except Diagnostic) Manufacturing. Sector: 32.