Member of the Technical Staff, Generative Models

Job overview

The Member of the Technical Staff, Generative Models role is listed onsite in San Francisco, CA, with a stated annual compensation range of $150,000–$350,000. Output Biosciences is developing biological reasoning models and therapies using AI and biology. The role leads the design, training, and evaluation of generative models that produce biologically grounded molecules. It spans research through model training, including architecture design, distributed GPU experiments, and evaluation of generated molecules for biological meaning, structural validity, and novelty.

What you'll do

• Design generative architectures for molecular data across modalities
• develop training approaches using biological signals
• build controllable generation methods for specified biological properties and chemical constraints
• integrate biological reasoning from the foundation model
• own experiment design and distributed multi-GPU training
• optimize hyperparameters
• and develop evaluation frameworks for biological meaning, structural validity, and novelty.

What we're looking for

Skills & competencies

generative models

machine learning

molecular data

biology

ai

san francisco ca

output biosciences

python

pytorch

distributed gpu training

research engineering

$150k–$350k

Work arrangement

• Weekend coverage required

Benefits & perks

• Equity, medical, dental, and vision coverage
• feedback-focused environment and day-to-day management ownership.

Why this role

Research-to-training ownership at a stealth AI-and-biotechnology startup; compensation includes salary and equity, as stated in the posting.

About the employer

Output Biosciences is hiring for this role. Industry: Research and Development in Biotechnology (except Nanobiotechnology). Sector: 54.