Senior Medical Director, Oncology Clinical Development

Job overview

The Senior Medical Director, Oncology Clinical Development role is onsite in Cambridge, MA, with travel up to 30%. The posting lists a base pay range of $292,000–$409,000 per year at commencement; additional compensation and benefits may include a sign-on bonus, restricted stock units, discretionary awards, and paid time off. Zai Lab is a biopharmaceutical company developing therapies for conditions including oncology. The medical director leads late-stage oncology clinical development, including pivotal Phase III and registration studies. The role provides medical oversight, supports regulatory and commercialization work, and coordinates cross-functional teams to advance oncology programs and protect patient safety.

What you'll do

• Lead design and execution of late-stage clinical trials
• serve as Medical Monitor
• review safety data and support monitoring activities
• contribute to clinical strategy, regulatory submissions, and lifecycle planning
• collaborate across regulatory, clinical operations, pharmacovigilance, biostatistics, medical affairs, and commercial teams
• represent the company externally
• analyze clinical and real-world data
• support business development and licensing activities.

What we're looking for

Skills & competencies

senior medical director

oncology

clinical development

phase iii trials

medical monitor

cambridge ma

zai lab

md

oncology board certification

up to 30% travel

$292k–$409k/year

Work arrangement

• Weekend coverage required

Benefits & perks

• Potential sign-on bonus, restricted stock units, and discretionary awards
• medical and financial benefits
• 401(k) eligibility
• vacation, sick time, and parental leave.

Why this role

Requires an MD with board certification in Oncology, Hematology-Oncology, or a related specialty, plus five years of clinical development experience focused on late-stage oncology trials; travel up to 30%.

About the employer

Zai Lab (US) LLC is hiring for this role. Industry: Research and Development in Biotechnology (except Nanobiotechnology). Sector: 54.