Senior Manager, Global Digital & Technology Systems Engineering

Job overview

The Senior Manager, Global Digital & Technology Systems Engineering role is onsite in San Mateo, CA. Compensation is not specified. The role supports BeOne Medicines’ Systems Engineering capability for research and development technology; BeOne develops drug therapies for cancer. This hands-on technical delivery role executes systems engineering work across R&D systems, external platforms, integrations, and foundational AI architectures. It helps deliver secure, compliant, supportable systems by coordinating with Enterprise IT, vendors, and R&D stakeholders.

What you'll do

• Execute systems engineering activities across R&D systems and platforms
• coordinate with Enterprise IT, vendors, and R&D stakeholders
• maintain technical and operational documentation
• support integrations, observability, deployment, lifecycle, and operational readiness
• implement assigned AI architecture components
• identify and escalate risks and dependencies
• support compliance and validation requirements.

What we're looking for

Skills & competencies

senior manager

systems engineering

digital technology

r&d systems

ai architecture

hybrid cloud

high-performance computing

san mateo ca

beone medicines

onsite

some travel expected

Work arrangement

• Weekend coverage required

Why this role

Combines R&D systems engineering with hybrid cloud, high-performance computing, and foundational AI implementation in a regulated pharmaceutical environment.

About the employer

BeOne Medicines is hiring for this role. Industry: Research and Development in Biotechnology (except Nanobiotechnology). Sector: 54.