Principal Scientist — Translational Data Science

Job overview

The Principal Scientist — Translational Data Science role is primarily onsite in Cambridge, MA, with a base salary range of $215,000–$245,000 per year. Parabilis Medicines is a clinical-stage biopharmaceutical company developing medicines for serious diseases, including programs targeting biologically important pathways. The scientist leads computational strategy for preclinical projects, integrating biological and disease data to inform target, mechanism, biomarker, and indication decisions. The role connects computational findings with experimental work and supports continuity of scientific rationale and data as projects advance into development programs.

What you'll do

• Lead translational data science for preclinical projects
• define computational strategies for project decisions
• integrate human genetics, tumor genomics, functional genomics, molecular profiling, preclinical studies, and other data
• partner with experimental scientists to develop testable hypotheses and prioritize experiments
• establish translational and biomarker hypotheses
• support project-to-program transitions and program analyses
• communicate recommendations to teams and leadership
• advance computational practices and mentor colleagues.

What we're looking for

Skills & competencies

principal scientist

translational data science

computational biology

oncology

drug discovery

biomarkers

tumor genomics

cambridge ma

$215k–$245k/year

parabilis medicines

Work arrangement

• Weekend coverage required

Benefits & perks

• Annual target bonus, equity, and a comprehensive benefits package.

Why this role

The posting seeks a PhD in a quantitative field and 10+ years of relevant industry experience, with deep oncology and computational biology expertise.

About the employer

Parabilis Medicines is hiring for this role. Industry: Biological Product (except Diagnostic) Manufacturing. Sector: 32.